产品货号：
Z38890
中文名称：
uPA/Urokinase/PLAU抗体
英文名称：
Anti-uPA/Urokinase/PLAU Antibody (Clone#OTI5H4)
产品规格：
50μl|100μl|150μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-uPA/Urokinase/PLAU Antibody (Clone#OTI5H4) |
| 指标别名 | ATF;PLAU;U plasminogen activator;uPA;uPA/Urokinase;URK |
| 克隆性 | Monoclonal |
| 检验物种 | human |
| 应用范围 | WB,IHC |
| 基因名称 | PLAU |
| 克隆号 | OTI5H4 |
| 抗体来源 | Mouse |
| 抗体类型 | IgG2a |
| 免疫原 | Human recombinant protein fragment corresponding to amino acids 107-379 of human PLAU (NP_002649) produced in E.coli. |
| 实际分子量 | 46.3KD |
| 成分 | PBS (PH 7.3) containing 1% BSA,50% glycerol and 0.02% sodium azide. |
| 纯化方式 | Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G) |
| 浓度 | 500μg/mL |
| 产品形态 | 溶液 |
| 保存条件 | Stable for 12 months from date of receipt.Store at -20℃ as received. |
| 背景资料 | This gene encodes a serine protease involved in degradation of the extracellular matrix and possibly tumor cell migration and proliferation.A specific polymorphism in this gene may be associated with late-onset Alzheimer's disease and also with decreased affinity for fibrin-binding.This protein converts plasminogen to plasmin by specific cleavage of an Arg-Val bond in plasminogen.Plasmin in turn cleaves this protein at a Lys-Ile bond to form a two-chain derivative in which a single disulfide bond connects the amino-terminal A-chain to the catalytically active,carboxy-terminal B-chain.This two-chain derivative is also called HMW-uPA (high molecular weight uPA).HMW-uPA can be further processed into LMW-uPA (low molecular weight uPA) by cleavage of chain A into a short chain A (A1) and an amino-terminal fragment.LMW-uPA is proteolytically active but does not bind to the uPA receptor.Alternatively spliced transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq,Feb 2009] |
| Uniprot ID | P00749 |
| 基因名全称 | plasminogen activator,urokinase |
| 蛋白名全称 | Urokinase-type plasminogen activator |
| 推荐稀释比 | Western blot (WB) 1:2000 Immunohistochemistry in paraffin section (IHC) 1:150 |
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